simultaneous

Reaction events (or reaction steps) can occur step by step. This relation can indicate a set of events that can occur at the same time.

His390 acts as a general base to activate water.
T1 AminoAcid 0 6 His390
T2 Deprotonation 17 29 general base
T3 Activation 33 41 activate
T4 OtherCompound 42 47 water
E1 Deprotonation:T2 Agent:T1 Theme:T4
E2 Activation:T3 Agent:T1 Theme:T4
* simultaneous E1 E2

However, in the following case, the relationships between the two events is coreference, instead of ‘simultaneous’, because the two same events are expressed differently.

His390 acts as a general base to deprotonate water.
T1 AminoAcid 0 6 His390
T2 Deprotonation 17 29 general base
T3 Deprotonation 33 44 deprotonate
T4 OtherCompound 45 50 water
E1 Deprotonation:T2 Agent:T1 Theme:T4
E2 Deprotonation:T3 Agent:T1 Theme:T4
R1 coreference Arg1:E2 Arg2:E1

The events which are associated by Coupling Reaction can also be related with ‘simultaneous’.

Specific binding is accompanied by conformational changes.
T1 Interaction 0 16 Specific binding
T2 CouplingReaction 20 31 accompanied
T3 ConformationalChange 35 57 conformational changes
E1 Interaction:T1
E2 CouplingReaction:T2 Theme:E3 Theme2:E1
E3 ConformationalChange:T3
* simultaneous E1 E3

More than two events can also be related with ‘simultaneous’.

Phosphoryl transfer is highly coupled to proton transfer.
T1 FunctionalGroup 0 10 Phosphoryl
T2 WholeReaction 11 19 transfer
T3 CouplingReaction 23 37 highly coupled
T4 Protonation 41 56 proton transfer
T5 Deprotonation 41 56 proton transfer
T6 FunctionalGroup 41 47 proton
E1 WholeReaction:T2 Theme:T1
E2 CouplingReaction:T3 Theme3:E1 Theme:E3 Theme2:E4
E3 Protonation:T4
E4 Deprotonation:T5
A1 ReactionType E1 Transfer
* simultaneous E1 E3 E4